Non-steroidal Anti-Inflammatory Drugs (NSAIDs)

Introduction

NSAIDs are anti-inflammatory medications commonly used to treat painful conditions in animals. Common NSAIDs include Rimadyl/Novox/Quellin (Carprofen), Metacam (Meloxicam), Deramaxx (Deracoxib), Etodolac (Etogesic), Aspirin, Zubrin (Tepoxalin), Previcox (Firocoxib), Grapiprant (Galliprant), and Robenacoxib (Onsior).

Missed doses and Changing medications

If you miss a dose of an NSAID, skip the missed dose and resume the regular dosing schedule. Do not administer a double dose.

Monitoring and Lab work

Prior to starting NSAID treatment, it is recommended to conduct blood work and urinalysis to check liver and kidney function. For pets on long-term NSAID therapy, these tests should be repeated twice a year to monitor for potential side effects such as subtle gastrointestinal bleeding, as well as liver and kidney issues.

Special precautions

NSAIDs should not be combined with steroid medications like prednisone. Ideally, your pet should be off steroids for several days before initiating NSAID therapy.

Potential side effects

While NSAIDs are generally safe, they can cause side effects. Contact your veterinarian immediately if you observe any of the following:

Inappetence: Urgent veterinary consultation is recommended.
Vomiting or Diarrhea: Particularly if it includes black, tar-like material or blood. This is an urgent concern.
Liver Issues: Liver problems can occur, although this is uncommon.
Kidney Disease: Use NSAIDs with caution in pets with kidney disease.
Usage in Cats: Caution is advised when using NSAIDs in cats. Generally, only Robenacoxib is recommended, and for a limited duration.